Haplotype analysis within quantitative trait locus affecting intramuscular fat content on porcine chromosome

S. Sato, C. Ohnishi, Y. Uemoto and E. Kobayashi
Additional contact information
S. Sato: National Livestock Breeding Center, Nishigo, Fukushima, Japan
C. Ohnishi: National Livestock Breeding Center, Nishigo, Fukushima, Japan
Y. Uemoto: National Livestock Breeding Center, Nishigo, Fukushima, Japan
E. Kobayashi: National Livestock Breeding Center, Nishigo, Fukushima, Japan

Czech Journal of Animal Science, 2011, vol. 56, issue 12, 521-528

Abstract: Previous results of fine mapping for quantitative trait loci affecting intramuscular fat content identified a 3.0-Mb chromosome interval on porcine chromosome 7, which contains at least 9 genes, based on the pig genome assembly. Therefore, we proposed these nine genes (LOC100154481, LOC100155711, LOC100155276, SPATA7, PTPN21, ZCH14, EML5, TTC8, and FOXN3) as positional candidate genes. The coding exons of the nine genes were characterized, and 45 polymorphisms were detected in F2 Duroc × Meishan population. Within the nine genes, 10 non-synonymous substitutions and 1 insertion were genotyped among three European breeds (Landrace, Large White, and Duroc) and 1 Chinese breed (Meishan). Genotyping data was used to perform the haplotype analysis. Polymorphisms were found in all the studied genes, except ZCH14. We surveyed the frequency of 33 haplotypes that formed non-synonymous substitutions in four breeds. One of them was distributed widely in the Landrace, Large White, and Meishan breeds, but not in Duroc. Each breed had different major haplotypes.

Keywords: pig; chromosome 7; intramuscular fat; positional candidate genes; polymorphism (search for similar items in EconPapers)
Date: 2011
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://cjas.agriculturejournals.cz/doi/10.17221/4414-CJAS.html (text/html)
http://cjas.agriculturejournals.cz/doi/10.17221/4414-CJAS.pdf (application/pdf)
free of charge

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjs:v:56:y:2011:i:12:id:4414-cjas

DOI: 10.17221/4414-CJAS

Access Statistics for this article

Czech Journal of Animal Science is currently edited by Bc. Michaela Polcarová

More articles in Czech Journal of Animal Science from Czech Academy of Agricultural Sciences
Bibliographic data for series maintained by Ivo Andrle ().