Effect of supplemental lactic acid bacteria on growth performance, glutathione turnover and aflatoxin B1 removal in lambs

Jianping Wang, Lin Lin, Qingrong Jiang, Wanli Huang and Ning Liu
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Lin Lin: Department of Animal Production, Henan University of Science and Technology, Luoyang, P.R. China
Qingrong Jiang: Department of Animal Production, Henan University of Science and Technology, Luoyang, P.R. China
Wanli Huang: Department of Animal Production, Henan University of Science and Technology, Luoyang, P.R. China
Ning Liu: Department of Animal Production, Henan University of Science and Technology, Luoyang, P.R. China

Czech Journal of Animal Science, 2019, vol. 64, issue 6, 272-278

Abstract: This study investigated the effect of lactic acid bacteria (LAB) on growth performance, glutathione turnover, aflatoxin B1 (AFB1) residue and AFB1-DNA adduct in growing lambs. Diets were a 2 × 2 factorial design, including AFB1 at 0 or 100 µg/kg and LAB at 0 or 3 × 109 cfu/kg. Results showed that AFB1 decreased (P < 0.05) feed intake (FI), body weight gain (BWG), and activities of glutathione (GSH), glutathione s-transferases (GSTs) and glutathione reductase (GR) in liver and duodenal mucosa, whereas these parameters were increased (P < 0.05) by supplemental LAB. AFB1 increased and LAB decreased the feed conversion ratio (P < 0.05). Interactions (P < 0.05) were found on BWG, liver GSTs and mucosal GSH. LAB decreased (P ≤ 0.001) AFB1 residue in liver, kidney, plasma and faeces and AFB1-DNA adduct in kidney, plasma and faeces. It can be concluded that LAB can partially protect against AFB1 toxicity by facilitating glutathione turnover and reducing AFB1 toxicity in lambs.

Keywords: aflatoxin B1-DNA adduct; aflatoxin B1 residue; body weight gain; feed conversion ratio; feed intake (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjs:v:64:y:2019:i:6:id:5-2019-cjas

DOI: 10.17221/5/2019-CJAS

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