Effect of carboxymethyl chito-oligosaccharide on cysteine absorption in intestinal porcine epithelial cells

Huayu Huang, Chen Zhang, Luqiu Feng, Naixiu Wang, Kai Wang, Zhenhui Song and Ling Gan
Additional contact information
Huayu Huang: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China
Chen Zhang: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China
Luqiu Feng: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China
Naixiu Wang: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China
Kai Wang: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China
Zhenhui Song: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China
Ling Gan: College of Veterinary Medicine, Southwest University, Chongqing, P.R. China

Czech Journal of Animal Science, 2022, vol. 67, issue 7, 266-274

Abstract: Oxidative stress is associated with retarded growth and the initiation and progression of diseases in pigs. The carboxymethylation of chito-oligosaccharide (COS) can improve its antioxidant activity for such issues. Herein, an orthogonal experiment L9 (34) test design was used to optimise the preparation conditions of carboxymethyl (CM)-COS. Fourier-transform infrared analysis evidenced the carboxymethylation of COS, and an in vitro study indicated that the hydroxyl radical scavenging ability of CM-COS is superior to that of COS. CM-COS can also better promote the absorption of cysteine and increase the expression of the amino acid transport system b0,+ in intestinal porcine epithelial cells. The results suggested that CM-COS can effectively resist oxidative damage by promoting cysteine absorption mediated by transport system b0,+, which provides important information regarding the antioxidative damage application of COS and CM-COS in the pig farming industry.

Keywords: carboxymethyl modification; antioxidant activity; amino acid transport system; intestinal health (search for similar items in EconPapers)
Date: 2022
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://cjas.agriculturejournals.cz/doi/10.17221/138/2021-CJAS.html (text/html)
http://cjas.agriculturejournals.cz/doi/10.17221/138/2021-CJAS.pdf (application/pdf)
free of charge

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjs:v:67:y:2022:i:7:id:138-2021-cjas

DOI: 10.17221/138/2021-CJAS

Access Statistics for this article

Czech Journal of Animal Science is currently edited by Bc. Michaela Polcarová

More articles in Czech Journal of Animal Science from Czech Academy of Agricultural Sciences
Bibliographic data for series maintained by Ivo Andrle ().