Multiple mammary tumours in a bitch: analysis of mitotic index, AgNOR count and c-erbB2 expression status: a case report

P. Kumar, R.V.S. Pawaiya and B.P. Madhu
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P. Kumar: Indian Veterinary Research Institute, Bareilly, India
R.V.S. Pawaiya: Indian Veterinary Research Institute, Bareilly, India
B.P. Madhu: Indian Veterinary Research Institute, Bareilly, India

Veterinární medicína, 2010, vol. 55, issue 12, 631-635

Abstract: This case report of multiple mammary tumours in a Spitz bitch revealed the presence of three tumour masses, T-1, T-2 and T-3, of variable size, shape and texture on different mammary glands. Histopathological examination revealed these tumours to be of different histological type (T-1 - fibrosarcoma, T-2 - malignant mixed mammary tumour and T-3 - papillary adenocarcinoma). The mitotic index and AgNOR count was high in all three tumours indicative of a higher proliferation status of neoplastic cells while T-2 and T-3 showed overexpression of the c-erbB2 oncoprotein.

Keywords: multiple mammary tumours; bitch; c-erbB2; AgNOR (search for similar items in EconPapers)
Date: 2010
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:55:y:2010:i:12:id:2949-vetmed

DOI: 10.17221/2949-VETMED

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