Human-to-human and human-to-dog Mycobacterium tuberculosis transmission studied by IS6110 RFLP analysis: a case report

M. Moravkova, M. Slany, I. Trcka, M. Havelkova, J. Svobodova, M. Skoric, B. Heinigeova and I. Pavlik
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M. Moravkova: Veterinary Research Institute, Brno, Czech Republic
M. Slany: Veterinary Research Institute, Brno, Czech Republic
I. Trcka: Veterinary Research Institute, Brno, Czech Republic
M. Havelkova: National Institute of Public Health, Prague, Czech Republic
J. Svobodova: Regional Institute of Public Health, Brno, Czech Republic
M. Skoric: University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
B. Heinigeova: Hospital Jindrichuv Hradec, Czech Republic
I. Pavlik: Veterinary Research Institute, Brno, Czech Republic

Veterinární medicína, 2011, vol. 56, issue 6, 314-317

Abstract: This study reports on the transmission of Mycobacterium tuberculosis of the same IS6110 RFLP type between two acquaintances with open pulmonary tuberculosis and a five-year-old Doberman bitch. No clinical signs, gross lesions at necropsy or histopathological lesions were observed in the infected lungs and gastrointestinal tract of the dog, although M. tuberculosis was directly detected by IS6110 PCR and culture examinations in the respiratory and gastrointestinal tracts. IS6110 PCR positivity in the faeces and blood of the dog poses a risk of M. tuberculosis transmission between the dog and humans.

Keywords: zoonosis; human tuberculosis; pet animal (search for similar items in EconPapers)
Date: 2011
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:56:y:2011:i:6:id:1547-vetmed

DOI: 10.17221/1547-VETMED

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