Cutaneous extrarenal rhabdoid tumor in a dog: a case report

H.J. Kim, E.J. Choi, H.R. Lee, B.T. Kwon and S.H. Do
Additional contact information
H.J. Kim: College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea
E.J. Choi: College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea
H.R. Lee: College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea
B.T. Kwon: Taejong Animal Hospital, Busan, Republic of Korea
S.H. Do: College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea

Veterinární medicína, 2015, vol. 60, issue 2, 115-119

Abstract: Rhabdoid tumours (RTs) are rare, highly aggressive tumours of undetermined origin in humans, and are sub-classified as renal/extrarenal RTs depending on location. The origins of extrarenal rhabdoid tumours are an enigma and neoplasms have rarely been reported in non-primate species. An 11-year-old male Maltese dog was presented with a submandibular mass. Histologically, the mass was composed of sheets of highly pleomorphic "rhabdoid" cells, further characterised by the presence of large epithelioid cells with globular/fibrillar paranuclear inclusions. Further immunohistochemical analysis revealed that the neoplastic cells were positive for vimentin and desmin similar to human tumours. In addition, ultrastructural analysis showed that the intracytoplasmic inclusions were mainly composed of whorled bundles of intermediate filaments. Our results suggest a useful diagnostic approach to cutaneous, extrarenal rhabdoid tumours in dogs and describe their characteristics.

Keywords: rhabdoid tumour; cutaneous; cytoplasmic inclusion; vimentin; transmission electron microscopy (search for similar items in EconPapers)
Date: 2015
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://vetmed.agriculturejournals.cz/doi/10.17221/7987-VETMED.html (text/html)
http://vetmed.agriculturejournals.cz/doi/10.17221/7987-VETMED.pdf (application/pdf)
free of charge

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:60:y:2015:i:2:id:7987-vetmed

DOI: 10.17221/7987-VETMED

Access Statistics for this article

Veterinární medicína is currently edited by Ing. Helena Smolová Ph.D.

More articles in Veterinární medicína from Czech Academy of Agricultural Sciences
Bibliographic data for series maintained by Ivo Andrle ().