Comparative use of dimethyl sulphoxide (DMSO) in different animal species

G.M. Madruga, L.Z. Crivellenti, S. Borin-Crivellenti, C.A. Cintra, L.G. Gomes and P.R. Spiller
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G.M. Madruga: Federal University of Mato Grosso (UFMT), Cuiaba, Brazil
L.Z. Crivellenti: Franca University (UNIFRAN), Franca, Brazil
S. Borin-Crivellenti: Franca University (UNIFRAN), Franca, Brazil
C.A. Cintra: Franca University (UNIFRAN), Franca, Brazil
L.G. Gomes: Federal University of Mato Grosso (UFMT), Cuiaba, Brazil
P.R. Spiller: Federal University of Mato Grosso (UFMT), Cuiaba, Brazil

Veterinární medicína, 2017, vol. 62, issue 4, 179-185

Abstract: Dimethyl sulphoxide has a variety of biological effects that have made it the subject of numerous pharmacological studies. The first dimethyl sulphoxide therapeutic indication approved by the United States Food and Drug Administration (FDA) in 1978 was for intravesical instillation in cases of interstitial cystitis. Since then, due to its distinctive properties, it has been the subject of studies in several areas. This review describes indications, adverse effects and contraindications, as takes a critical approach to the main articles addressing the clinical use of dimethyl sulphoxide.

Keywords: dimethyl sulfoxide; indications; adverse effects; contraindications; interstitial cystitis; therapeutic properties; cryopreservation; DMSO toxicity; experimental models (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:62:y:2017:i:4:id:176-2015-vetmed

DOI: 10.17221/176/2015-VETMED

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