Biochemical profile of urine in guinea pigs (Cavia porcellus)

H Cernochova, A Hundakova, E Bardi and Z Knotek
Additional contact information
H Cernochova: Avian and Exotic Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic
A Hundakova: Avian and Exotic Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic
E Bardi: Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Milan, Milano, Italy
Z Knotek: Avian and Exotic Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic

Veterinární medicína, 2020, vol. 65, issue 10, 445-450

Abstract: Guinea pigs are common patients in veterinary clinics. Knowledge of the urine composition is necessary for the evaluation of their health. We, therefore, analysed the urine of fifty guinea pigs, thirty-two males, and eighteen females, aged between four months and seven years. None of these guinea pigs showed clinical signs of urinary tract diseases. The urine samples were obtained as part of a preventive check-up, during a regular dental check-up or another minor procedure. The urine was acquired by spontaneous micturition after inducing a short-term, light isoflurane anaesthesia. A macroscopic evaluation of the urine samples and a urine dipstick test were used for the preliminary examination. The average pH was determined to be 8.5 ± 0.5, and in three animals, moderate glycosuria was detected using the urine dipsticks. No urobilinogen, ketone bodies, haemoglobin, or blood traces were present in any of the samples. Severe proteinuria was detected in all the samples. The samples were subsequently evaluated in a laboratory for the following values: specific gravity 1 024.40 ± 1.83 kg/m3, osmolality 601.14 ± 52.28 mOsm/kg, total protein 290.16 ± 34.73 mg/l, albumin 12.04 ± 1.92 mg/l, glucose 0.77 ± 0.20 mmol/l, urea 217.60 ± 24.23 mmol/l, creatinine 3.98 ± 0.48 mmol/l, bilirubin 9.63 ± 1.73 μmol/l, calcium 6.14 ± 0.40 mmol/l, phosphorus 4.95 ± 1.30 mmol/l, magnesium 9.86 ± 0.57 mmol/l, sodium 49.15 ± 6.67 mmol/l, potassium 152.21 ± 10.62 mmol/l, chloride 51.14 ± 5.81 mmol/l, activity of gamma-glutamyltransferase 0.72 ± 0.14 μkat/l, alkaline phosphatase 0.56 ± 0.11 μkat/l and lactate dehydrogenase 0.68 ± 0.14 μkat/l. The descriptive values of the urine biochemical parameters of guinea pigs were determined for the first time in this study.

Keywords: clinical biochemistry; herbivorous mammals; urinalysis (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://vetmed.agriculturejournals.cz/doi/10.17221/32/2020-VETMED.html (text/html)
http://vetmed.agriculturejournals.cz/doi/10.17221/32/2020-VETMED.pdf (application/pdf)
free of charge

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:65:y:2020:i:10:id:32-2020-vetmed

DOI: 10.17221/32/2020-VETMED

Access Statistics for this article

Veterinární medicína is currently edited by Ing. Helena Smolová Ph.D.

More articles in Veterinární medicína from Czech Academy of Agricultural Sciences
Bibliographic data for series maintained by Ivo Andrle ().