Treatment of a feline cutaneous mast cell tumour using imatinib mesylate as a neoadjuvant tyrosine kinase inhibitor therapeutic agent

J Kim and Kim Hj
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J Kim: Department of Veterinary Internal Medicine, Chonnam National University, Yongbong-ro, Buk-gu, Gwangju, Republic of Korea
Kim Hj: Department of Veterinary Internal Medicine, Chonnam National University, Yongbong-ro, Buk-gu, Gwangju, Republic of Korea

Veterinární medicína, 2020, vol. 65, issue 2, 84-88

Abstract: A two-year-old spayed female American shorthair cat presented with a rough, circular, exophytic mass on the genital area. The clinical findings and histopathological examination revealed that the mass contained neoplastic mast cells and, thus, was diagnosed as a mast cell tumour. The anatomical location of the mass was not easily accessible for surgical intervention. We administered a targeted therapy using oral imatinib mesylate for eight weeks to reduce the size of the lesion and to facilitate the successful surgical removal. The tumour mass eventually reduced by 21% and was surgically excised. This is possibly the first study to use imatinib mesylate as a tumour reduction neoadjuvant to therapeutically address a feline cutaneous mast cell tumour located in a surgically inaccessible part of the body.

Keywords: feline; mast cell tumour; chemotherapy; tyrosine kinase inhibitor (search for similar items in EconPapers)
Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:65:y:2020:i:2:id:91-2019-vetmed

DOI: 10.17221/91/2019-VETMED

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