Successful management of feline CD4+ CD8+ T-cell mediastinal lymphoma with pericardial effusion

Yu Sj, Kim He, Han Hj and Kim Jh
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Yu Sj: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwangjin-gu, Seoul, Republic of Korea
Kim He: Department of Veterinary Internal Medicine, Konkuk University Veterinary Medical Teaching Hospital, Gwangjin-gu, Seoul, Republic of Korea
Han Hj: Veterinary Emergency Medicine and Critical Care, Konkuk University Veterinary Medical Teaching Hospital, Gwangjin-gu, Seoul, Republic of Korea
Kim Jh: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwangjin-gu, Seoul, Republic of Korea

Veterinární medicína, 2022, vol. 67, issue 10, 544-551

Abstract: A 2-year-old, castrated, male Russian blue cat presented with acute dyspnoea, cyanosis, and lethargy. A thoracic radiography revealed a large cranial mediastinal mass; the computed tomography revealed caudal lobe atelectasis of the right lung with pericardial and pleural effusions. The cytodiagnostic tests revealed high-grade CD4+ CD8+ T-cell mediastinal lymphoma as clinical stage Vb; l-asparaginase-cyclophosphamide-doxorubicin-vincristine-prednisolone (l-CHOP)-based chemotherapy was initiated, following which the mass shrunk rapidly; 1 week after the initiation of chemotherapy, the appetite-related and respiratory symptoms improved dramatically, and the pleural and pericardial effusion resolved. The patient remains in complete remission three years after the initiation of the l-CHOP chemotherapy. Therefore, the accurate diagnosis and instantaneous initiation of chemotherapy may resolve life-threatening pleural and pericardial effusions in cats with high-grade aberrant T-cell mediastinal lymphoma.

Keywords: cat; flow cytometry; l-CHOP; multi-agent chemotherapy; pleural effusion (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlvet:v:67:y:2022:i:10:id:70-2021-vetmed

DOI: 10.17221/70/2021-VETMED

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