Triazole as a Privileged Scaffold: Recent Progress in Antibacterial and Antifungal Drug Development

Nivrutti Ambadkar, Kishore Puri and Santosh B. Gaikwad

International Journal of Scientific Research in Chemistry, 2026, vol. 11, issue 4, 37-46

Abstract: The triazole scaffold is a crucial component of heterocyclic chemistry, serving as a basic building block in organic synthesis, materials science, and medicinal chemistry. Triazole is a five membered ring composed of three nitrogen atoms and two carbon atoms, and it exists in two isomeric forms: 1,2,3-triazole and 1,2,4-triazole. Compounds featuring the triazole ring are important heterocycles known for their diverse biological activities, including antimicrobial, antiproliferative, antimalarial, anticonvulsant, anti-inflammatory, antineoplastic, antiviral, analgesic, and anticancer properties. As a result, triazole derivatives have attracted significant attention from researchers. This review aims to provide a thorough overview of the published studies on the synthesis of triazole derivatives, highlighting various methods for obtaining the triazole moiety. These methods include classical approaches as well as microwave and ultrasound-assisted techniques.

Keywords: heterocyclic; 1,2,3-triazole; 1,2,4-triazole; green chemistry; Medicinal chemistry (search for similar items in EconPapers)
Date: 2026
Note: Article URL: https://ijsrch.com/home/article/view/IJSRCH241145
References: Add references at CitEc
Citations:

Downloads: (external link)
https://ijsrch.com/home/article/view/IJSRCH241145 Article URL (text/html)
https://ijsrch.com/home/article/download/IJSRCH241145/IJSRCH241145 Full text (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:cuo:ijsrch:v11:y2026:i4:id:101

DOI: 10.32628/IJSRCH241145

Access Statistics for this article

More articles in International Journal of Scientific Research in Chemistry from International Journal of Scientific Research in Chemistry
Bibliographic data for series maintained by Pankaj Sharma ().