Effect of Vitreoretinal Surgery Combined with Platelet-Rich Plasma on the Quality of Life of Patients with Macular Hole

Kyrykbayev

Health Leadership and Quality of Life, 2025, vol. 4, 820

Abstract: Introduction: this study evaluates the impact of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling and platelet-rich plasma (PRP) application on anatomical, functional, and quality-of-life (QoL) outcomes in patients with macular holes. Method: prospective cohort study. Tertiary eye care center, January 2021 to December 2023. A total of 155 patients underwent PPV with ILM peeling and PRP. Visual acuity (logMAR), macular hole closure, and QoL were assessed pre- and postoperatively. QoL evaluation used a localized adaptation of the NEI VFQ-25 questionnaire. Anatomical outcomes were measured by Optical Coherence Tomography (OCT). Results: the mean age was 65,90 ± 8,84 years; 38 % were female. The closure rate was 94 %. Visual acuity improved significantly, with average logMAR improving from 0,7 to 0,3 (p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:dbk:health:v:4:y:2025:i::p:820:id:820

DOI: 10.56294/hl2025820

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