Expression and Prognostic Relevance of LncRNA GSEC in HNSC: Focus on OSCC

Deleheibateer, Od Bayarsaikhan, Ganbayar Batmunkh, Xu Wu, Xingan Zhou and Shiirevnyamba Avirmed

Seminars in Medical Writing and Education, 2025, vol. 4, 708

Abstract: Background: Bioinformatics identified HNSC diagnostic/prognostic lncRNAs; GSEC was selected for HNSC/OSCC validation. Methods: HNSC transcriptomic/clinical data from TCGA identified differentially expressed lncRNAs. Univariate Cox regression found prognostic lncRNAs. The top 30 lncRNAs from random forest ranking intersected with Cox results selected diagnostic biomarkers. Xiantao Academic performed pan-cancer analysis of GSEC. UALCAN and Kaplan-Meier analyzed GSEC expression, clinical correlation, prognosis, and Xiantao Academic assessed immune infiltration in HNSC. Top 200 GSEC co-expressed genes (FDR

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:dbk:medicw:v:4:y:2025:i::p:708:id:708

DOI: 10.56294/mw2025708

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