EconPapers    
Economics at your fingertips  
 

Partition clustering of high dimensional low sample size data based on p-values

George von Borries and Haiyan Wang

Computational Statistics & Data Analysis, 2009, vol. 53, issue 12, 3987-3998

Abstract: Clustering techniques play an important role in analyzing high dimensional data that is common in high-throughput screening such as microarray and mass spectrometry data. Effective use of the high dimensionality and some replications can help to increase clustering accuracy and stability. In this article a new partitioning algorithm with a robust distance measure is introduced to cluster variables in high dimensional low sample size (HDLSS) data that contain a large number of independent variables with a small number of replications per variable. The proposed clustering algorithm, PPCLUST, considers data from a mixture distribution and uses p-values from nonparametric rank tests of homogeneous distribution as a measure of similarity to separate the mixture components. PPCLUST is able to efficiently cluster a large number of variables in the presence of very few replications. Inherited from the robustness of rank procedure, the new algorithm is robust to outliers and invariant to monotone transformations of data. Numerical studies and an application to microarray gene expression data for colorectal cancer study are discussed.

Date: 2009
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/S0167-9473(09)00241-2
Full text for ScienceDirect subscribers only.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:csdana:v:53:y:2009:i:12:p:3987-3998

Access Statistics for this article

Computational Statistics & Data Analysis is currently edited by S.P. Azen

More articles in Computational Statistics & Data Analysis from Elsevier
Bibliographic data for series maintained by Catherine Liu ().

 
Page updated 2025-03-19
Handle: RePEc:eee:csdana:v:53:y:2009:i:12:p:3987-3998