An approach to the treatment evaluation of Hodgkin's disease

P Aspden, Sbj Sutcliffe, Ar Timothy and Rrp Jackson

Omega, 1981, vol. 9, issue 5, 537-546

Abstract: Hodgkin's disease is a cancer of the lymphatic system. The major feature influencing the type of treatment employed, and the ultimate prognosis, is the stage or extent of disease prior to therapy. This paper is concerned with evaluating the difference in patient progress of two staging procedures. One (pathological staging) procedure is more extensive than the other (clinical staging). The evaluation is carried out by firstly developing a mathematical model of patient progress for pathologically staged patients and then using this model to predict what would have happened to clinically staged patients if they had been treated according to their pathological stage. Comparison of these predictions with actual results suggests that pathologically staged patients appear to remain in disease free survival (remission) following radio-therapy longer than clinically staged patients.

Date: 1981
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