 Sensitivity analysis study on the effect of the fluid mechanics assumptions for the computation of electrical conductivity of flowing human bloodGian Marco Melito, Müller, Thomas Stephan, Vahid Badeli, Katrin Ellermann, Brenn, Günter and Reinbacher-Köstinger, Alice Reliability Engineering and System Safety, 2021, vol. 213, issue C Abstract: Impedance cardiography is a non-invasive methodology for measuring cardiodynamic parameters, such as stroke volume and heart rate, as well as cardiac output. For the measurement, the electric conductivity of blood is important. The conductivity of blood depends on various parameters, such as the haematocrit value as well as the red blood cells’ (RBC) shape and orientation. In models, the response is usually affected by uncertainty, which may lead to inaccurate medical diagnosis. Therefore, a ranking of the influence of the model’s input factors may be necessary. Also, physically and physiologically correct assumptions are fundamental for the accuracy of the model. The basis for predicting the conductivity of blood in this study is the Maxwell–Fricke theory, which allows computing the electrical bulk conductivity of quiescent blood. For flowing blood, fluid mechanics has to be coupled in the modelling phase. Keywords: Sensitivity analysis; Blood conductivity; Fluid mechanics; Polynomial chaos expansion (search for similar items in EconPapers) Downloads: (external link) Related works: Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text Persistent link: https://EconPapers.repec.org/RePEc:eee:reensy:v:213:y:2021:i:c:s0951832021002040 DOI: 10.1016/j.ress.2021.107663 Access Statistics for this article Reliability Engineering and System Safety is currently edited by Carlos Guedes Soares More articles in Reliability Engineering and System Safety from Elsevier |
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