An index of the ratio of inflammatory to antiviral cell types mediates the effects of social adversity and age on chronic illness

Ronald L. Simons, Man-Kit Lei, Steven R.H. Beach, Ashley B. Barr, Carolyn E. Cutrona, Frederick X. Gibbons and Robert A. Philibert

Social Science & Medicine, 2017, vol. 185, issue C, 158-165

Abstract: It is assumed that both social stress and chronological age increase the risk of chronic illness, in part, through their effect on systemic inflammation. Unfortunately, observational studies usually employ single-marker measures of inflammation (e.g., Interleukin-6, C-reactive protein) that preclude strong tests for mediational effects.

Keywords: Social determinants of health; Inflammation; Accelerated aging; Socioeconomic adversity; Chronic illness (search for similar items in EconPapers)
Date: 2017
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Citations: View citations in EconPapers (3)

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DOI: 10.1016/j.socscimed.2017.03.005

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