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Imperfect biomarkers for adjuvant chemotherapy in early stage breast cancer with good prognosis

Catherine Bourgain, Lionel Pourtau, Chafika Mazouni, Martine Bungener and et Julia Bonastre

Social Science & Medicine, 2020, vol. 246, issue C

Abstract: The proliferation of biomarkers has raised concerns regarding the possibility for clinical judgment to be improperly removed from clinician's jurisdiction and included in laboratory tests. To evaluate the ways in which the diffusion of biomarkers questions the autonomy of clinicians, we consider the case of chemotherapy prescription to women with early stage breast cancer and a good prognosis. Drawing on a qualitative study of clinicians working in a diversity of institutional contexts, we follow three biomarkers available to guide this routinely made decision.

Date: 2020
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DOI: 10.1016/j.socscimed.2019.112735

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