Does crime trigger genetic risk for type 2 diabetes in young adults? A G x E interaction study using national data

Fangqi Guo, Kathleen Mullan Harris, Jason D. Boardman and Jennifer W. Robinette

Social Science & Medicine, 2022, vol. 313, issue C

Abstract: Living in neighborhoods perceived as disordered exacerbates genetic risk for type 2 diabetes (T2D) among older adults. It is unknown whether this gene-neighborhood interaction extends to younger adults. The present study aims to investigate whether crime, an objectively measured indicator of neighborhood disorder, triggers genetic risk for T2D among younger adults, and whether this hypothesized triggering occurs through exposure to obesity.

Keywords: Crime; Neighborhood; Type 2 diabetes; Polygenic scores; G x E; Obesity (search for similar items in EconPapers)
Date: 2022
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DOI: 10.1016/j.socscimed.2022.115396

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