Evaluating the psychosocial experiences of participants in HIV cure research before, during, and after analytical treatment interruptions: A longitudinal qualitative study in the United States

Miranda Hill, Lidia Rodriguez Garcia, Elizabeth Nguyen, Anastasia Korolkova, Lillian Cohn, Antonio Rodriguez, Rebecca Hoh, Steven G. Deeks, Michael J. Peluso, John A. Sauceda and Karine Dubé

Social Science & Medicine, 2025, vol. 366, issue C

Abstract: The lack of socio-behavioral research on stress and psychosocial experiences among research participants who undergo analytical treatment interruption (ATI) in HIV cure studies underscores a critical gap in cure science. Existing literature acknowledges mixed and potentially adverse mental health impacts of ATIs among trial participants, but empirical insights before, during, and after clinical studies are scarce. We used longitudinal in-depth interviews with 11 participants in HIV cure-related research to explore their experiences with stress, coping, and psychological well-being before, during, and after an ATI.

Keywords: HIV cure research; Analytical treatment interruptions; Psychosocial experiences; Stress; Coping; Research ethics; People with HIV (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:eee:socmed:v:366:y:2025:i:c:s0277953624010980

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DOI: 10.1016/j.socscimed.2024.117644

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