Influence of sex on the incidence of colorectal cancer: considering the influence of gender mechanisms

Amalia Martinez, Nadine Hamieh, Hélène Colineaux, Michelle Kelly-Irving, Pascale Grosclaude, Emmanuel Wiernik, Cyrille Delpierre and Sébastien Lamy

Social Science & Medicine, 2025, vol. 376, issue C

Abstract: Differences in colorectal cancer (CRC) incidence between men and women are documented, but the role of gender mechanisms in explaining these disparities remains underexplored. CRC, the third deadliest cancer worldwide, is often analyzed through “biological” sex differences, without a clear distinction between innate and socially acquired factors. Gender mechanisms, including social roles, behaviors, and access to healthcare, may significantly influence CRC risk.

Keywords: Colorectal cancer; Gender mechanisms; Health inequalities –social determinants; Mediation analysis; Social epidemiology (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:eee:socmed:v:376:y:2025:i:c:s0277953625003880

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DOI: 10.1016/j.socscimed.2025.118058

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