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Racial inequities in the incidence of major adverse cardiovascular events in ELSA-Brasil cohort: the mediating role of weathering

Amanda Viana Machado, Sandhi Maria Barreto, Rodrigo Citton Padilha dos Reis, Luana Giatti, Sheila Maria Alvim Matos, Ana Luísa Patrão, Belinda L. Needham and Lidyane V. Camelo

Social Science & Medicine, 2025, vol. 383, issue C

Abstract: The weathering hypothesis proposes that chronic exposure to social disadvantage leads to earlier onset of age-related diseases, explaining, in part, greater CVD disadvantages of racialized groups. The investigation of such a hypothesis is incipient in Brazil, a society strongly marked by racism. We investigated whether racism is associated with incidence of major adverse cardiovascular events (MACE) and the extent to which weathering explained this association in Brazilian adults.

Keywords: Racism; Cardiovascular diseases; Biological age; Weathering; Causal mediation analysis (search for similar items in EconPapers)
Date: 2025
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DOI: 10.1016/j.socscimed.2025.118421

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