Maintenance of diversity in a hierarchical host–parasite model with balancing selection and reinfection

Cornelia Pokalyuk and Anton Wakolbinger

Stochastic Processes and their Applications, 2020, vol. 130, issue 2, 1119-1158

Abstract: Inspired by DNA data of the human cytomegalovirus we propose a model of a two-type parasite population distributed over its hosts. The parasite is capable to persist in its host till the host dies, and to reinfect other hosts. To maintain type diversity within a host, balancing selection is assumed.

Keywords: Hierarchical host–parasite system; Balancing selection; Mean-field limit; Random genealogies (search for similar items in EconPapers)
Date: 2020
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DOI: 10.1016/j.spa.2019.04.009

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