Semiparametric inference of treatment effects on restricted mean survival time in two sample problems from length-biased samples

Xiaoran Yang, Junjie Du and Fangfang Bai

Statistics & Probability Letters, 2023, vol. 193, issue C

Abstract: Estimating treatment effects on restricted mean survival time(RMST) is often of direct interest in clinical studies. We propose two approaches based on estimating equation to estimate treatment effects on RMST under the setting of length-biased sampling. The asymptotic properties for the proposed estimators are derived. Simulation studies are performed to evaluate the performance of the methods in finite sample sizes. In addition, we apply our procedures to Oscar Award data.

Keywords: Length-biased data; Restricted mean survival time; Semiparametric inference; Treatment effect; Two sample problem (search for similar items in EconPapers)
Date: 2023
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DOI: 10.1016/j.spl.2022.109715

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