Modelling heterogeneity for bivariate survival data by the log-normal distribution

David D. Hanagal

Statistics & Probability Letters, 2008, vol. 78, issue 9, 1101-1109

Abstract: We propose a bivariate Weibull regression model with heterogeneity (frailty or random effect) which is generated by log-normal distribution. We assume that the bivariate survival data follow bivariate Weibull of [Hanagal, D.D., 2004. Parametric bivariate regression analysis based on censored samples: A Weibull model. Economic Quality Control 19, 83--90]. There are some interesting situations like survival times in genetic epidemiology, dental implants of patients and twin births (both monozygotic and dizygotic) where genetic behaviour (which is unknown and random) of patients follows known frailty distribution. These are the situations which motivate to study this particular model. We propose two-stage maximum likelihood estimation for hierarchical likelihood in the proposed model. We present a small simulation study to compare these estimates with the true value of the parameters and it is observed that these estimates are very close to the true values of the parameters. We also compare theoretical standard errors with Monte Carlo standard errors and theoretical coverage probabilities with Monte Carlo coverage probabilities.

Date: 2008
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/S0167-7152(07)00380-X
Full text for ScienceDirect subscribers only

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:stapro:v:78:y:2008:i:9:p:1101-1109

Ordering information: This journal article can be ordered from
http://www.elsevier.com/wps/find/supportfaq.cws_home/regional
https://shop.elsevie ... _01_ooc_1&version=01

Access Statistics for this article

Statistics & Probability Letters is currently edited by Somnath Datta and Hira L. Koul

More articles in Statistics & Probability Letters from Elsevier
Bibliographic data for series maintained by Catherine Liu ().