Finding quantitative trait loci genes with collaborative targeted maximum likelihood learning

Hui Wang, Sherri Rose and Mark J. van der Laan

Statistics & Probability Letters, 2011, vol. 81, issue 7, 792-796

Abstract: Quantitative trait loci mapping is focused on identifying the positions and effect of genes underlying an observed trait. We present a collaborative targeted maximum likelihood estimator in a semi-parametric model using a newly proposed 2-part super learning algorithm to find quantitative trait loci genes in listeria data. Results are compared to the parametric composite interval mapping approach.

Keywords: Collaborative; targeted; maximum; likelihood; estimation; Quantitative; trait; loci; Super; learner; Machine; learning (search for similar items in EconPapers)
Date: 2011
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Citations: View citations in EconPapers (2)

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