Microemulsion Systems: Generalities and Fields of Application

Fernández R. Nathalie, Madrigal R. German, Chavarría R. Marianela, Matarrita B. Daniela, Baltodano V. Eleaneth, Carazo B. Gustavo and Pacheco M. Jorge
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Fernández R. Nathalie: University of Costa Rica, Costa Rica
Madrigal R. German: University of Costa Rica, Costa Rica
Chavarría R. Marianela: University of Costa Rica, Costa Rica
Matarrita B. Daniela: University of Costa Rica, Costa Rica
Baltodano V. Eleaneth: University of Costa Rica, Costa Rica
Carazo B. Gustavo: University of Costa Rica, Costa Rica
Pacheco M. Jorge: University of Costa Rica, Costa Rica

European Journal of Pharmaceutical Research, 2023, vol. 3, issue 4, 14-22

Abstract: Microemulsions are two-phase oil-aqueous systems stabilized by a surfactant/cosurfactant system, formed from the spontaneous self-assembly of hydrophobic or hydrophilic parts of surfactant molecules, essential at the industrial level for their unique properties, improving processes and reducing costs. Their main uses in the pharmaceutical, cosmetic, and food industries are to improve the biopharmaceutical and pharmacokinetic properties of drugs, the skin penetration properties, and the stability and solubility of different ingredients. They are obtained by techniques such as phase inversion and phase titration. They are characterized by different techniques that allow obtaining information on the dynamic properties, droplet size, structural arrangement and orientation, molecular aggregation, and system interactions, which allow improving the formulations continuously. Due to their proven advantages and utilities, as well as their potential applications, it is essential to study these systems.

Keywords: Bioavailability; formulation; microemulsions; solubility; surfactants (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:epw:pharma:v:3:y:2023:i:4:id:765

DOI: 10.24018/ejpharma.2023.3.4.65

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