Advances in Ginger–Boswellic Acid Nanoemulgels for Enhanced Topical Delivery in Osteoarthritis Management

Nitin Kumar, Indu Mittal and Iram Rajput

International Journal of Scientific Research in Science and Technology, 2025, vol. 12, issue 6, 263-271

Abstract: Osteoarthritis (OA) is a common degenerative joint disease characterized by progressive cartilage degradation and persistent inflammation . The search for safer, more focused therapeutic options is necessary because standard pharmacological treatments, especially oral non-steroidal anti-inflammatory drugs (NSAIDs), carry risks of serious systemic side effects . This review investigates the development of a novel nanoemulgel formulation combining boswellic acid and ginger, two herbal bioactives with strong anti-inflammatory properties. By employing a nanoscopic oil-in-water emulsion within a hydrogel base, the nanoemulgel platform effectively tackles the main challenge of topical delivery—the skin's barrier function . Providing a comprehensive approach to pain and inflammation management. The article also covers important formulation details, such as excipient selection and preparation methods, and gives a summary of crucial characterization tests, such as rheology, particle size, zeta potential, and different efficacy studies . The evidence that is currently available indicates that the ginger-boswellic acid nanoemulgel is a potentially effective non-invasive treatment for osteoarthritis.

Keywords: Osteoarthritis; Nanoemulgel; Topical Drug Delivery; Ginger; Boswellic Acid; Anti- inflammatory; Herbal Medicine (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:etm:ijsrst:v12:y2025:i6:id:1284

DOI: 10.32628/IJSRST25126326

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