Diagnostics for Targeted NSCLC Therapy

Verena Schildgen, Ilija Nenadic, Michael Brockmann and Oliver Schildgen
Additional contact information
Verena Schildgen: Kliniken der Stadt Köln gGmbH, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, D-51109 Cologne, Germany
Ilija Nenadic: Kliniken der Stadt Köln gGmbH, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, D-51109 Cologne, Germany
Michael Brockmann: Kliniken der Stadt Köln gGmbH, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, D-51109 Cologne, Germany
Oliver Schildgen: Kliniken der Stadt Köln gGmbH, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, D-51109 Cologne, Germany

Challenges, 2017, vol. 8, issue 2, 1-6

Abstract: Despite an increasing number of molecular biomarkers identified in non-small cell lung cancer (NSCLC), the number of approved therapy options targeting these biomarkers remains limited. Although some biomarkers may influence the therapy outcome of a distinct drug and have been shown to be useful in phase 2 or 3 clinical studies, diagnostics of biomarkers without an approved drug available or a possible off-label use is currently too expensive for routine diagnostics in non-academic institutions. For this reason, the present review is intended to summarize the current state of the art of molecular diagnostics that is both available and could lead to therapy guidance in NSCLC courses. Thereby, economic aspects are taken into account in order to take up the cudgels for a more comprehensive, even if more expensive, diagnostic scheme that in turn may save enormous costs by reducing therapy costs.

Keywords: lung cancer; NSCLC; diagnostics (search for similar items in EconPapers)
JEL-codes: A00 C00 Z00 (search for similar items in EconPapers)
Date: 2017
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/2078-1547/8/2/29/pdf (application/pdf)
https://www.mdpi.com/2078-1547/8/2/29/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jchals:v:8:y:2017:i:2:p:29-:d:119640

Access Statistics for this article

Challenges is currently edited by Ms. Karen Sun

More articles in Challenges from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().