Chlamydospore Specific Proteins of Candida albicans

Sujata Ingle, Santosh Kodgire, Asha Shiradhone, Rajendra Patil and Gajanan Zore
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Sujata Ingle: School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded 431606, MS, India
Santosh Kodgire: School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded 431606, MS, India
Asha Shiradhone: School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded 431606, MS, India
Rajendra Patil: Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune 411007, MS, India
Gajanan Zore: School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded 431606, MS, India

Data, 2017, vol. 2, issue 3, 1-5

Abstract: Polymorphic yeast, Candida albicans , forms thick-walled structures called chlamydospores in order to survive under adverse conditions. We present proteomic profile changes occurring during chlamydospore formation. Chlamydospores were induced by inoculating C. albicans cells (grown for 48 h) on rice extract and semisolid agar containing tween 80 (1%), and were overlaid by a polyethene sheet to induce microaerophilic conditions at 30 °C. Proteins extracted from chlamydospores and hyphae (producing chlamydospores) were identified by LC-MS/MS analysis. Present datasets include proteomic data (Swath spectral libraries) of chlamydospores and yeast phase cells, as well as methodologies and tools used for the data generation. Further analysis is expected to provide an opportunity to understand modulations in metabolic processes, molecular architecture (i.e., cell wall, membrane, and cytoskeleton) and stress response pathways leading to chlamydospore formation and thus facilitating survival of C. albicans under adverse conditions.

Keywords: C. albicans; chlamydospore; metabolism; cell wall; LC-MS (search for similar items in EconPapers)
JEL-codes: C8 C80 C81 C82 C83 (search for similar items in EconPapers)
Date: 2017
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