Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)—A Randomized Controlled Lifestyle Trial

Tiia Ngandu, Jenni Lehtisalo, Esko Levälahti, Tiina Laatikainen, Jaana Lindström, Markku Peltonen, Alina Solomon, Satu Ahtiluoto, Riitta Antikainen, Tuomo Hänninen, Antti Jula, Francesca Mangialasche, Teemu Paajanen, Satu Pajala, Rainer Rauramaa, Timo Strandberg, Jaakko Tuomilehto, Hilkka Soininen and Miia Kivipelto
Additional contact information
Tiia Ngandu: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Jenni Lehtisalo: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Esko Levälahti: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Tiina Laatikainen: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Jaana Lindström: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Markku Peltonen: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Alina Solomon: Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor, SE-14157 Stockholm, Sweden
Satu Ahtiluoto: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Riitta Antikainen: Institute of Health Sciences/Geriatrics, University of Oulu, and Oulu University Hospital, P.O. Box 5000, FI-90014 University of Oulu, Finland
Tuomo Hänninen: Department of Neurology, Kuopio University Hospital, P.O. Box 100, FI-70029 KYS, Kuopio, Finland
Antti Jula: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Francesca Mangialasche: Aging Research Center, Karolinska Institutet—Stockholm University, Gävlegatan 16, SE-11330 Stockholm, Sweden
Teemu Paajanen: Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland
Satu Pajala: Department of Lifestyle and Participation, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
Rainer Rauramaa: Kuopio Research Institute of Exercise Medicine, Kuopion yliopisto, Haapaniementie 16, 70100 Kuopio, Finland
Timo Strandberg: Institute of Health Sciences/Geriatrics, University of Oulu, and Oulu University Hospital, P.O. Box 5000, FI-90014 University of Oulu, Finland
Jaakko Tuomilehto: Department of Public Health, University of Helsinki, P.O. Box 40, FI-00014 University of Helsinki, Finland
Hilkka Soininen: Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland
Miia Kivipelto: Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland

IJERPH, 2014, vol. 11, issue 9, 1-16

Abstract: Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) study population. Potential study participants (age 60–77 years, the dementia risk score ?6) were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited (n = 5496), 48% (n = 2654) attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1). The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD) age of the randomized participants was 69.4 (4.7) years, Mini-Mental State Examination 26.7 (2.0) points, systolic blood pressure 140.1 (16.2) mmHg, total serum cholesterol 5.2 (1.0) mmol/L for, and fasting glucose 6.1 (0.9) mmol/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons.

Keywords: cognitive impairment; dementia; Alzheimer’s disease; lifestyle; intervention; randomized controlled trial (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2014
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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