Body Mass Index (BMI) Is Associated with Microalbuminuria in Chinese Hypertensive Patients

Xinyu Liu, Yu Liu, Youming Chen, Yongqiang Li, Xiaofei Shao, Yan Liang, Bin Li, Harry Holthöfer, Guanjing Zhang and Hequn Zou
Additional contact information
Xinyu Liu: Institute of Nephrology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
Yu Liu: Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou 510623, China
Youming Chen: Clinical Laboratory Centre, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
Yongqiang Li: Institute of Nephrology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
Xiaofei Shao: Institute of Nephrology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
Yan Liang: Institute of Nephrology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
Bin Li: Institute of Nephrology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
Harry Holthöfer: Centre for Bio Analytical Sciences (CBAS), Dublin City University, Dublin 9, Ireland
Guanjing Zhang: Techco Information Technologies Co., Ltd., Shenzhen 518057, China
Hequn Zou: Institute of Nephrology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China

IJERPH, 2015, vol. 12, issue 2, 1-11

Abstract: There is no general consensus on possible factors associated with microalbuminuria in hypertensive patients nor any reported study about this issue in Chinese patients. To examine this issues, 944 hypertensive patients were enrolled in a study based on a cross-sectional survey conducted in Southern China. Multivariate regression analyses were performed to identify the factors related with the presence of microalbuminuria and urinary excretion of albumin. The prevalence of microalbuminuria in hypertensive and non-diabetic hypertensive patients were 17.16% and 15.25%, respectively. Body mass index (BMI), but not waist circumference (WC), were independently associated with microalbuminuria and the values of urinary albumin to creatinine ratio (ACR) based on multiple regression analyses, even after excluding diabetic patients and patients taking inhibitors of the renin-angiotensin system from the analyses. Furthermore, patients with obesity (BMI ?28) had higher levels of ACR, compared with those with normal weight (BMI <24 kg/m 2 ) and overweight (24 kg/m 2 ? BMI < 28). In conclusion, BMI, as a modifiable factor, is closely associated with microalbuminuria among Chinese hypertensive patients, which may provide a basis for future development of intervention approaches for these patients.

Keywords: hypertension; mircroalbuminuria; BMI (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2015
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.mdpi.com/1660-4601/12/2/1998/pdf (application/pdf)
https://www.mdpi.com/1660-4601/12/2/1998/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:12:y:2015:i:2:p:1998-2008:d:45701

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().