Association between Air Pollutants and Cardiovascular Disease Mortality in Wuhan, China

Yisi Liu, Xi Chen, Shuqiong Huang, Liqiao Tian, Yuan'an Lu, Yan Mei, Meng Ren, Na Li, Li Liu and Hao Xiang
Additional contact information
Yisi Liu: School of Public Health, Wuhan University, Wuhan 430071, Hubei Province, China
Xi Chen: School of Public Health, Wuhan University, Wuhan 430071, Hubei Province, China
Shuqiong Huang: Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, Hubei Province, China
Liqiao Tian: State Key Laboratory of Information Engineering in Surveying, Mapping and Remote Sensing, Wuhan University, Wuhan 430079, China
Yuan'an Lu: Environmental Health Laboratory, Department of Public Health Sciences, Univ Hawaii at Manoa, 1960 East West Rd., Biomed Bldg., D105, Honolulu, HI 96822, USA
Yan Mei: School of Stomatology, Wuhan University, Wuhan 430071, Hubei Province, China
Meng Ren: School of Public Health, Wuhan University, Wuhan 430071, Hubei Province, China
Na Li: School of Public Health, Wuhan University, Wuhan 430071, Hubei Province, China
Li Liu: Department of Epidemiology and Biostatistics, Guangdong Key Lab of Molecular Epidemiology, School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, China
Hao Xiang: School of Public Health, Wuhan University, Wuhan 430071, Hubei Province, China

IJERPH, 2015, vol. 12, issue 4, 1-11

Abstract: We examined the associations of daily mean concentrations of ambient air pollutants (particulate matter (PM 10 ), sulfur dioxide (SO 2 ), nitric oxide (NO 2 )) and daily cardiovascular diseases (CVD) mortality in Wuhan, China using a case-crossover design to analyze four years of data (2006–2009) collected from the Hubei Provincial Center for Disease Control and Prevention and the Wuhan Environmental Protection Bureau. From 2006 to 2009, daily average concentrations of PM 10 , SO 2 and NO 2 were 115.60 µg/m 3 , 53.21 µg/m 3 and 53.08 µg/m 3 , respectively. After adjusting for temperature and relative humidity, a 10 µg/m 3 increase in SO 2 and NO 2 over a 24-h period was associated with CVD mortality relative risk (R.R.) of 1.010 (95% CI: 1.000, 1.020) for SO 2 and 1.019 (95% CI: 1.005, 1.033) for NO 2 , but there was no significant association between increases in PM 10 and mortality. Subgroup analysis on by gender showed a significant association of 1.026 (95% CI: 1.007, 1.045) between NO 2 and CVD among males, while no significant statistical effect was shown among females. Subgroup analysis by age showed that for those older than 65 years, every 10 µg/m 3 increase in NO 2 was associated with a 1.6% (95% CI: 0.1%, 3.1%) increase in CVD mortality. Subgroup analysis on different types of CVD showed that every 10 µg/m 3 increase in PM 10 and SO 2 were significantly associated with an approximately 1.012 (95% CI: 1.002, 1.022) and 1.021 (95% CI: 1.002, 1.040) increase, respectively, in ischemic heart disease (ICH) mortality. In conclusion, exposure to NO 2 is significantly associated with CVD mortality. Larger, multi-center studies in Chinese cities are being currently conducted to validate these findings.

Keywords: PM 10; NO 2; SO 2; cardiovascular disease; mortality (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2015
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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