Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents

Jimmy T. Efird, William F. Griffin, Daniel F. Sarpong, Stephen W. Davies, Iulia Vann, Nathaniel T. Koutlas, Ethan J. Anderson, Patricia B. Crane, Hope Landrine, Linda Kindell, Zahra J. Iqbal, T. Bruce Ferguson, W. Randolph Chitwood and Alan P. Kypson
Additional contact information
Jimmy T. Efird: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
William F. Griffin: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
Daniel F. Sarpong: Center for Minority Health and Health Disparities Research and Education, Xavier University of Louisiana, New Orleans, LA 70125, USA
Stephen W. Davies: Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
Iulia Vann: Department of Public Health, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
Nathaniel T. Koutlas: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
Ethan J. Anderson: Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
Patricia B. Crane: The College of Nursing, East Carolina University, Greenville, NC 27834, USA
Hope Landrine: Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
Linda Kindell: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
Zahra J. Iqbal: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
T. Bruce Ferguson: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
W. Randolph Chitwood: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA
Alan P. Kypson: Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, USA

IJERPH, 2015, vol. 12, issue 7, 1-13

Abstract: The aim of this study was to examine racial differences in long-term mortality after coronary artery bypass grafting (CABG), stratified by preoperative use of inotropic agents. Black and white patients who required preoperative inotropic support prior to undergoing CABG procedures between 1992 and 2011 were compared. Mortality probabilities were computed using the Kaplan-Meier product-limit method. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. A total of 15,765 patients underwent CABG, of whom 211 received preoperative inotropic agents within 48 hours of surgery. Long-term mortality differed by race (black versus white) among preoperative inotropic category (inotropes: adjusted HR = 1.6, 95% CI = 1.009–2.4; no inotropes: adjusted HR = 1.15, 95% CI = 1.08–1.2; P interaction < 0.0001). Our study identified an independent preoperative risk-factor for long-term mortality among blacks receiving CABG. This outcome provides information that may be useful for surgeons, primary care providers, and their patients.

Keywords: inotropes; cardiac surgery; mortality; disparities; heart disease; heart failure (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2015
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/12/7/7478/pdf (application/pdf)
https://www.mdpi.com/1660-4601/12/7/7478/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:12:y:2015:i:7:p:7478-7490:d:52109

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().