Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico

Gerónimo Maldonado-Martínez, Robert F. Hunter-Mellado, Diana Fernández-Santos and Eddy Ríos-Olivares
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Gerónimo Maldonado-Martínez: Data Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico
Robert F. Hunter-Mellado: Internal Medicine Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico
Diana Fernández-Santos: Data Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico
Eddy Ríos-Olivares: Microbiology Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico

IJERPH, 2015, vol. 13, issue 1, 1-8

Abstract: The introduction of antiretroviral therapy (ART) has allowed human immunodeficiency virus (HIV) suppression in patients. We present data of a cohort of Puerto Rican patients with HIV who were under treatment with a steady regime of ART across a time horizon of eleven years. The time periods were categorized into four year stratums: 2000 to 2002; 2003 to 2005; 2006 to 2008 and 2009 to 2011. Socio-demographic profile, HIV risk factors, co-morbid conditions were included as study variables. One year mortality was defined. The p value was set at ?0.05. The cohort consisted of 882 patients with 661 subjects presenting with persistent HIV viral load after a self-reported 12 month history of ART use. In this sub-cohort a higher viral load was seen across time ( p < 0.05). Illicit drug use, IV drug use, alcohol use, loss of work were associated to having higher viral load means ( p < 0.05). HIV viral load mean was lower as BMI increased ( p < 0.001). It is imperative to readdress antiretroviral adherence protocols and further study ART tolerance and compliance.

Keywords: HIV; viremia; mean viral load; ART; Puerto Rico (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2015
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