Independent Factors of Changes of Ankle-Brachial Index in Peripheral Arterial Occlusive Disease in Elderly Patients with or without Diabetes

Ewelina Bąk, Czesław Marcisz, Monika Kadłubowska, Anna Michalik, Bożena Krawczyk, Dorota Dobrzyń-Matusiak, Sylwia Krzemińska, Tomasz Fiałkowski, Elżbieta Glądys and Agnieszka Drosdzol-Cop
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Ewelina Bąk: Faculty of Health Sciences, University of Bielsko-Biala, 43-309 Bielsko-Biala, Poland
Czesław Marcisz: Department of Gerontology and Geriatric Nursing, School of Health Sciences, Medical University of Silesia, 40-752 Katowice, Poland
Monika Kadłubowska: Faculty of Health Sciences, University of Bielsko-Biala, 43-309 Bielsko-Biala, Poland
Anna Michalik: Faculty of Health Sciences, University of Bielsko-Biala, 43-309 Bielsko-Biala, Poland
Bożena Krawczyk: Faculty of Health Sciences, University of Bielsko-Biala, 43-309 Bielsko-Biala, Poland
Dorota Dobrzyń-Matusiak: Department of Nursing Propaedeutics, School of Health Sciences, Medical University of Silesia, 40-752 Katowice, Poland
Sylwia Krzemińska: Department of Clinical Nursing Faculty of Health Sciences, Medical University, 50-367 Wroclaw, Poland
Tomasz Fiałkowski: Department of Rehabilitation, Medical University, Provincial Hospital in Bielsko-Biala, 43-309 Bielsko-Biala, Poland
Elżbieta Glądys: Specialist Psychiatric Health Care Center, 43-309 Bielsko-Biala, Poland
Agnieszka Drosdzol-Cop: School of Health Sciences in Katowice, Medical University of Silesia, Chair of Woman’s Health, 40-752 Katowice, Poland

IJERPH, 2016, vol. 13, issue 11, 1-11

Abstract: Peripheral arterial disease (PAD) belongs to the commonly-occurring pathologies associated with elderly age. A simple tool for defining the severity of PAD is the ankle-brachial index (ABI). The purpose of this research was to determine independent factors of changes of ABI in elderly patients with occlusive PAD disease (PAOD) with and without diabetes. The research was carried out on 49 elderly patients with PAOD, including 29 patients with type 2 diabetes, and 20 patients without diabetes. The concentration of interleukin-6 (IL-6), E-selectin, fibrinogen, and C-reactive protein (CRP) in the blood serum was marked. In all patients, the independent factors of changes of ABI were determined with the use of the multiple logistic regression analysis. Our results show that in the group of patients with PAOD suffering from diabetes, it was demonstrated that the ABI was related to age, the duration of the symptoms of PAD, body mass index (BMI), low-density lipoprotein cholesterol, fibrinogen, and sex (determination coefficient R 2 = 0.699). In patients with PAOD without diabetes, the ABI was related to age, the duration of the symptoms of PAD, the levels of CRP, E-selectin, high-density lipoprotein cholesterol, and the glomerular filtration rate(determination coefficient R 2 = 0.844). We conclude that in elderly patients with PAOD with and without diabetes, the participation of independent factors related to the ABI is diversified; in patients with diabetes, the concentration of IL-6 and fibrinogen is lower, and the concentration of E-selectin is higher than in patients without diabetes.

Keywords: ankle-brachial index; peripheral arterial disease; diabetes; elderly (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2016
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