Estimation of the Human Extrathoracic Deposition Fraction of Inhaled Particles Using a Polyurethane Foam Collection Substrate in an IOM Sampler

Darrah K. Sleeth, Susan A. Balthaser, Scott Collingwood and Rodney R. Larson
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Darrah K. Sleeth: Rocky Mountain Center for Occupational & Environmental Health, Department of Family & Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
Susan A. Balthaser: Rocky Mountain Center for Occupational & Environmental Health, Department of Family & Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
Scott Collingwood: Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
Rodney R. Larson: Rocky Mountain Center for Occupational & Environmental Health, Department of Family & Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA

IJERPH, 2016, vol. 13, issue 3, 1-14

Abstract: Extrathoracic deposition of inhaled particles ( i.e. , in the head and throat) is an important exposure route for many hazardous materials. Current best practices for exposure assessment of aerosols in the workplace involve particle size selective sampling methods based on particle penetration into the human respiratory tract ( i.e. , inhalable or respirable sampling). However, the International Organization for Standardization (ISO) has recently adopted particle deposition sampling conventions (ISO 13138), including conventions for extrathoracic (ET) deposition into the anterior nasal passage (ET 1 ) and the posterior nasal and oral passages (ET 2 ). For this study, polyurethane foam was used as a collection substrate inside an inhalable aerosol sampler to provide an estimate of extrathoracic particle deposition. Aerosols of fused aluminum oxide (five sizes, 4.9 µm–44.3 µm) were used as a test dust in a low speed (0.2 m/s) wind tunnel. Samplers were placed on a rotating mannequin inside the wind tunnel to simulate orientation-averaged personal sampling. Collection efficiency data for the foam insert matched well to the extrathoracic deposition convention for the particle sizes tested. The concept of using a foam insert to match a particle deposition sampling convention was explored in this study and shows promise for future use as a sampling device.

Keywords: extrathoracic deposition; polyurethane foam; IOM sampler; inhalable particles; oral passage; nasal passage (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2016
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