Environmental Risk Factors in Psoriasis: The Point of View of the Nutritionist

Luigi Barrea, Francesca Nappi, Carolina Di Somma, Maria Cristina Savanelli, Andrea Falco, Anna Balato, Nicola Balato and Silvia Savastano
Additional contact information
Luigi Barrea: I.O.S. & COLEMAN Srl, 80011 Naples, Italy
Francesca Nappi: I.O.S. & COLEMAN Srl, 80011 Naples, Italy
Carolina Di Somma: IRCCS SDN, Napoli Via Gianturco 113, 80143 Naples, Italy
Maria Cristina Savanelli: I.O.S. & COLEMAN Srl, 80011 Naples, Italy
Andrea Falco: I.O.S. & COLEMAN Srl, 80011 Naples, Italy
Anna Balato: Dipartimento di Medicina Clinica e Chirurgia, Unit of Dermatology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131 Naples, Italy
Nicola Balato: Dipartimento di Medicina Clinica e Chirurgia, Unit of Dermatology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131 Naples, Italy
Silvia Savastano: Dipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131 Naples, Italy

IJERPH, 2016, vol. 13, issue 7, 1-12

Abstract: Psoriasis is a common, chronic, immune-mediated skin disease with systemic pro-inflammatory activation, where both environmental and genetic factors contribute to its pathogenesis. Among the risk factors for psoriasis, evidence is accumulating that nutrition plays a major role, per se, in psoriasis pathogenesis. In particular, body weight, nutrition, and diet may exacerbate the clinical manifestations, or even trigger the disease. Understanding the epidemiological relationship between obesity and psoriasis is also important for delineating the risk profile for the obesity-related comorbidities commonly found among psoriatic patients. Moreover, obesity can affect both drug’s pharmacokinetics and pharmacodynamics. Additionally, the overall beneficial effects on the obesity-associated comorbidities, clinical recommendations to reduce weight and to adopt a healthy lifestyle could improve the psoriasis severity, particularly in those patients with moderate to severe disease, thus exerting additional therapeutic effects in the conventional treatment in obese patients with psoriasis. Education regarding modifiable environmental factors is essential in the treatment of this disease and represents one of the primary interventions that can affect the prognosis of patients with psoriasis. The goal is to make psoriatic patients and health care providers aware of beneficial dietary interventions. The aim of this review is to assess the relevance of the environmental factors as modifiable risk factors in psoriasis pathogenesis, with particular regard to the involvement of obesity and nutrition in the management of psoriasis, providing also specific nutrition recommendations.

Keywords: environmental risk factors; nutritionist; obesity; body composition; bioelectrical impedance analysis; phase angle; lifestyle; nutrition; Mediterranean diet (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2016
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