Efficacy of a Low Dose of Hydrogen Peroxide (Peroxy Ag + ) for Continuous Treatment of Dental Unit Water Lines: Challenge Test with Legionella pneumophila Serogroup 1 in a Simulated Dental Unit Waterline

Savina Ditommaso, Monica Giacomuzzi, Elisa Ricciardi and Carla M. Zotti
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Savina Ditommaso: Department of Public Health and Pediatrics, University of Turin, Turin 10126, Italy
Monica Giacomuzzi: Department of Public Health and Pediatrics, University of Turin, Turin 10126, Italy
Elisa Ricciardi: Department of Public Health and Pediatrics, University of Turin, Turin 10126, Italy
Carla M. Zotti: Department of Public Health and Pediatrics, University of Turin, Turin 10126, Italy

IJERPH, 2016, vol. 13, issue 7, 1-10

Abstract: This study was designed to examine the in vitro bactericidal activity of hydrogen peroxide against Legionella . We tested hydrogen peroxide (Peroxy Ag + ) at 600 ppm to evaluate Legionella survival in a simulated dental treatment water system equipped with Water Hygienization Equipment (W.H.E.) device that was artificially contaminated. When Legionella pneumophila serogroup (sg) 1 was exposed to Peroxy Ag + for 60 min we obtained a two decimal log reduction. High antimicrobial efficacy was obtained with extended periods of exposure: four decimal log reduction at 75 min and five decimal log reduction at 15 h of exposure. Involving a simulation device (Peroxy Ag + is flushed into the simulation dental unit waterlines (DUWL)) we obtained an average reduction of 85% of Legionella load. The product is effective in reducing the number of Legionella cells after 75 min of contact time (99.997%) in the simulator device under test conditions. The Peroxy Ag + treatment is safe for continuous use in the dental water supply system (i.e., it is safe for patient contact), so it could be used as a preventive option, and it may be useful in long-term treatments, alone or coupled with a daily or periodic shock treatment.

Keywords: Legionella; disinfectants; dental infection control; hydrogen peroxide (H 2 O 2 ); biofilm; microbial sensitivity test (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2016
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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