Comparison of the Ability to Predict Mortality between the Injury Severity Score and the New Injury Severity Score: A Meta-Analysis

Qiangyu Deng, Bihan Tang, Chen Xue, Yuan Liu, Xu Liu, Yipeng Lv and Lulu Zhang
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Qiangyu Deng: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China
Bihan Tang: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China
Chen Xue: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China
Yuan Liu: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China
Xu Liu: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China
Yipeng Lv: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China
Lulu Zhang: Department of Military Health Management, College of Health Service, Second Military Medical University, 800 Xiangyin Rd., Shanghai 200433, China

IJERPH, 2016, vol. 13, issue 8, 1-12

Abstract: Background: Description of the anatomical severity of injuries in trauma patients is important. While the Injury Severity Score has been regarded as the “gold standard” since its creation, several studies have indicated that the New Injury Severity Score is better. Therefore, we aimed to systematically evaluate and compare the accuracy of the Injury Severity Score and the New Injury Severity Score in predicting mortality. Methods: Two researchers independently searched the PubMed, Embase, and Web of Science databases and included studies from which the exact number of true-positive, false-positive, false-negative, and true-negative results could be extracted. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies checklist criteria. The meta-analysis was performed using Meta-DiSc. Meta-regression, subgroup analyses, and sensitivity analyses were conducted to determine the source(s) of heterogeneity and factor(s) affecting the accuracy of the New Injury Severity Score and the Injury Severity Score in predicting mortality. Results: The heterogeneity of the 11 relevant studies (total n = 11,866) was high (I 2 > 80%). The meta-analysis using a random-effects model resulted in sensitivity of 0.64, specificity of 0.93, positive likelihood ratio of 5.11, negative likelihood ratio of 0.27, diagnostic odds ratio of 27.75, and area under the summary receiver operator characteristic curve of 0.9009 for the Injury Severity Score; and sensitivity of 0.71, specificity of 0.87, positive likelihood ratio of 5.22, negative likelihood ratio of 0.20, diagnostic odds ratio of 24.74, and area under the summary receiver operating characteristic curve of 0.9095 for the New Injury Severity Score. Conclusion: The New Injury Severity Score and the Injury Severity Score have similar abilities in predicting mortality. Further research is required to determine the appropriate use of the Injury Severity Score or the New Injury Severity Score based on specific patient condition and trauma type.

Keywords: Injury Severity Score; New Injury Severity Score; mortality; meta-analysis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2016
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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