Genotypic and Epidemiological Trends of Acute Gastroenteritis Associated with Noroviruses in China from 2006 to 2016

Shu-Wen Qin, Ta-Chien Chan, Jian Cai, Na Zhao, Zi-Ping Miao, Yi-Juan Chen and She-Lan Liu
Additional contact information
Shu-Wen Qin: Department of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Ta-Chien Chan: Center for Geographic Information Science, Research Center for Humanities and Social Sciences, Academia Sinica, Taipei 115, Taiwan
Jian Cai: Department of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Na Zhao: CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
Zi-Ping Miao: Department of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Yi-Juan Chen: Department of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
She-Lan Liu: Department of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China

IJERPH, 2017, vol. 14, issue 11, 1-15

Abstract: There are periodical norovirus-associated acute gastroenteritis outbreaks around the world. This study aimed to analyze the molecular and epidemiological features of norovirus infections in China during 2006–2016. We extracted epidemiological data from 132 norovirus outbreaks and the norovirus genotyping for 1291 sequences in China over the past ten years. A total of 132 norovirus outbreaks (8133 cases) were reported in China, where the east and south regions were most affected [47.7% (63/132)]. The highest number of outbreaks occurred in 2015. A seasonal pattern has been observed, with a peak from November to the following March. Most of the outbreaks occurred in middle and primary schools, accounting for 28.8% (38/132), and 28.0% (37/132) of outbreaks, respectively. The dominant age group was 10 to 19 years old, responsible for 75.7% (933/1232) of cases. Generally, the dominant genotypes was GII, for 81.9% (1058/1291) of sequences. G II.4 was the predominant genotype in China from 2004 to 2014. However, the GII.17 became more prevalent starting in 2014. Norovirus-associated acute gastroenteritis increased sharply in recent years caused by the emergence of GII.17, but epidemiological features have not changed during 2006–2016. Vigilant surveillance should be strengthened to promptly detect any variation.

Keywords: norovirus; epidemiology; genotyping; acute gastroenteritis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/14/11/1341/pdf (application/pdf)
https://www.mdpi.com/1660-4601/14/11/1341/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:14:y:2017:i:11:p:1341-:d:117518

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().