New Immunotherapy Strategies in Breast Cancer

Lin-Yu Yu, Jie Tang, Cong-Min Zhang, Wen-Jing Zeng, Han Yan, Mu-Peng Li and Xiao-Ping Chen
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Lin-Yu Yu: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
Jie Tang: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
Cong-Min Zhang: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
Wen-Jing Zeng: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
Han Yan: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
Mu-Peng Li: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China
Xiao-Ping Chen: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, China

IJERPH, 2017, vol. 14, issue 1, 1-18

Abstract: Breast cancer is the most commonly diagnosed cancer among women. Therapeutic treatments for breast cancer generally include surgery, chemotherapy, radiotherapy, endocrinotherapy and molecular targeted therapy. With the development of molecular biology, immunology and pharmacogenomics, immunotherapy becomes a promising new field in breast cancer therapies. In this review, we discussed recent progress in breast cancer immunotherapy, including cancer vaccines, bispecific antibodies, and immune checkpoint inhibitors. Several additional immunotherapy modalities in early stages of development are also highlighted. It is believed that these new immunotherapeutic strategies will ultimately change the current status of breast cancer therapies.

Keywords: breast cancer; immunotherapy; cancer vaccines; bispecific antibodies; immune checkpoint inhibitors; stimulatory molecule agonists (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2017
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