Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China

Ruixue Xia, Guopeng Zhou, Tong Zhu, Xueying Li and Guangfa Wang
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Ruixue Xia: Department of Respiratory Medicine, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China
Guopeng Zhou: Department of Hospital Information, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China
Tong Zhu: State Key Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing 100871, China
Xueying Li: Department of Hospital Information, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China
Guangfa Wang: Department of Respiratory Medicine, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China

IJERPH, 2017, vol. 14, issue 4, 1-11

Abstract: Air pollutants are associated with cardiovascular death; however, there is limited evidence of the effects of different pollutants on out-of-hospital cardiac arrests (OHCAs) in Beijing, China. We aimed to investigate the associations of OHCAs with the air pollutants PM 2.5–10 (coarse particulate matter), PM 2.5 (particles ≤2.5 μm in aerodynamic diameter), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ), carbon monoxide (CO), and ozone (O 3 ) between 2013 and 2015 using a time-stratified case-crossover study design. We obtained health data from the nationwide emergency medical service database; 4720 OHCA cases of cardiac origin were identified. After adjusting for relative humidity and temperature, the highest odds ratios of OHCA for a 10 μg/m 3 increase in PM 2.5 were observed at Lag Day 1 (1.07; 95% confidence interval (CI): 1.04–1.10), with strong associations with advanced age (aged ≥70 years) (1.09; 95% CI: 1.05–1.13) and stroke history (1.11; 95% CI: 1.06–1.16). PM 2.5–10 and NO 2 also showed significant associations with OHCAs, whereas SO 2 , CO, and O 3 had no effects. After simultaneously adjusting for NO 2 and SO 2 in a multi-pollutant model, PM 2.5 remained significant. The effects of PM 2.5 in the single-pollutant models for cases with hypertension, respiratory disorders, diabetes mellitus, and heart disease were higher than those for cases without these complications; however, the differences were not statistically significant. The results support that elevated PM 2.5 exposure contributes to triggering OHCA, especially in those who are advanced in age and have a history of stroke.

Keywords: air pollution; out-of-hospital cardiac arrest; case-crossover study; Beijing; fine particulate matter (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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