Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China

Ruixue Xia, Guopeng Zhou, Tong Zhu, Xueying Li and Guangfa Wang
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Ruixue Xia: Department of Respiratory Medicine, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China
Guopeng Zhou: Department of Hospital Information, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China
Tong Zhu: State Key Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing 100871, China
Xueying Li: Department of Hospital Information, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China
Guangfa Wang: Department of Respiratory Medicine, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China

IJERPH, 2017, vol. 14, issue 4, 1-11

Abstract: Air pollutants are associated with cardiovascular death; however, there is limited evidence of the effects of different pollutants on out-of-hospital cardiac arrests (OHCAs) in Beijing, China. We aimed to investigate the associations of OHCAs with the air pollutants PM 2.5–10 (coarse particulate matter), PM 2.5 (particles ?2.5 ?m in aerodynamic diameter), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ), carbon monoxide (CO), and ozone (O 3 ) between 2013 and 2015 using a time-stratified case-crossover study design. We obtained health data from the nationwide emergency medical service database; 4720 OHCA cases of cardiac origin were identified. After adjusting for relative humidity and temperature, the highest odds ratios of OHCA for a 10 ?g/m 3 increase in PM 2.5 were observed at Lag Day 1 (1.07; 95% confidence interval (CI): 1.04–1.10), with strong associations with advanced age (aged ?70 years) (1.09; 95% CI: 1.05–1.13) and stroke history (1.11; 95% CI: 1.06–1.16). PM 2.5–10 and NO 2 also showed significant associations with OHCAs, whereas SO 2 , CO, and O 3 had no effects. After simultaneously adjusting for NO 2 and SO 2 in a multi-pollutant model, PM 2.5 remained significant. The effects of PM 2.5 in the single-pollutant models for cases with hypertension, respiratory disorders, diabetes mellitus, and heart disease were higher than those for cases without these complications; however, the differences were not statistically significant. The results support that elevated PM 2.5 exposure contributes to triggering OHCA, especially in those who are advanced in age and have a history of stroke.

Keywords: air pollution; out-of-hospital cardiac arrest; case-crossover study; Beijing; fine particulate matter (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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