Association between Exposure to Ambient Air Particulates and Metabolic Syndrome Components in a Saudi Arabian Population

Magdy Shamy, Mansour Alghamdi, Mamdouh I. Khoder, Abdullah M. Mohorjy, Alser A. Alkhatim, Abdulrahman K. Alkhalaf, Jason Brocato, Lung Chi Chen, George D. Thurston, Chris C. Lim and Max Costa
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Magdy Shamy: Department of Environmental Sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Mansour Alghamdi: Department of Environmental Sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Mamdouh I. Khoder: Department of Environmental Sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Abdullah M. Mohorjy: Department of Civil Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Alser A. Alkhatim: Department of Environmental Sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Abdulrahman K. Alkhalaf: Department of Meteorology, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Jason Brocato: Department of Environmental Medicine, New York University School of Medicine, New York, NY 10987, USA
Lung Chi Chen: Department of Environmental Medicine, New York University School of Medicine, New York, NY 10987, USA
George D. Thurston: Department of Environmental Medicine, New York University School of Medicine, New York, NY 10987, USA
Chris C. Lim: Department of Environmental Medicine, New York University School of Medicine, New York, NY 10987, USA
Max Costa: Department of Environmental Medicine, New York University School of Medicine, New York, NY 10987, USA

IJERPH, 2017, vol. 15, issue 1, 1-11

Abstract: Recent epidemiological evidence suggests that exposure to particulates may be a factor in the etiology of metabolic syndrome (MetS). In this novel study, we investigated the relationship between particulate levels and prevalence of MetS component abnormalities (hypertension, hyperglycemia, obesity) in a recruited cohort (N = 2025) in Jeddah, Saudi Arabia. We observed significant associations between a 10 μg/m 3 increase in PM 2.5 and increased risks for MetS (Risk Ratio (RR): 1.12; 95% Confidence Interval (CI): 1.06–1.19), hyperglycemia (RR: 1.08; 95% CI: 1.03–1.14), and hypertension (RR: 1.09; 95% CI: 1.04–1.14). PM 2.5 from soil/road dust was found to be associated with hyperglycemia (RR: 1.12; 95% CI: 1.06–1.19) and hypertension (RR: 1.11; 95% CI: 1.05–1.18), while PM 2.5 from traffic was associated with hyperglycemia (RR: 1.33; 95% CI: 1.05–1.71). We did not observe any health associations with source-specific mass exposures. Our findings suggest that exposure to specific elemental components of PM 2.5 , especially Ni, may contribute to the development of cardiometabolic disorders.

Keywords: air pollution; particulate matter; metabolic syndrome; hypertension; diabetes; hyperglycemia (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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