Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women

Anna Walentukiewicz, Anna Lysak-Radomska, Joanna Jaworska, Krzysztof Prusik, Katarzyna Prusik, Jakub Antoni Kortas, Marcin Lipiński, Anna Babinska, Jedrzej Antosiewicz and Ewa Ziemann
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Anna Walentukiewicz: Faculty of Rehabilitation and Kinesiology, Department of Health Promotion and Posturology, Gdansk University of Physical Education and Sport, K. Gorskiego 1, 80-336 Gdansk, Poland
Anna Lysak-Radomska: Faculty of Rehabilitation and Kinesiology, Department of Physiotherapy, Gdansk University of Physical Education and Sport, K. Gorskiego 1, 80-336 Gdansk, Poland
Joanna Jaworska: Faculty of Rehabilitation and Kinesiology, Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gorskiego 1, 80-336 Gdansk, Poland
Krzysztof Prusik: Faculty of Tourism and Recreation, Department of Health Promotion, Gdańsk, Gdansk University of Physical Education and Sport, K. Gorskiego 1, 80-336 Gdansk, Poland
Katarzyna Prusik: Faculty of Tourism and Recreation, Department of Health Promotion, Gdańsk, Gdansk University of Physical Education and Sport, K. Gorskiego 1, 80-336 Gdansk, Poland
Jakub Antoni Kortas: Faculty of Tourism and Recreation, Department of Health Promotion, Gdańsk, Gdansk University of Physical Education and Sport, K. Gorskiego 1, 80-336 Gdansk, Poland
Marcin Lipiński: Department of Biochemistry, Medical University of Gdańsk, M. Skłodowskiej-Curie 3, 80-001 Gdansk; Poland
Anna Babinska: Department of Endocrinology and Internal Medicine, Medical University of Gdańsk, M. Sklodowskiej-Curie 3, 80-001 Gdansk, Poland
Jedrzej Antosiewicz: Department of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, M. Sklodowskiej-Curie 3, 80-001 Gdansk, Poland
Ewa Ziemann: Faculty of Rehabilitation and Kinesiology, Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gorskiego 1, 80-336 Gdansk, Poland

IJERPH, 2018, vol. 15, issue 10, 1-13

Abstract: The aim of the study was to verify if coupling 12 weeks of vitamin D supplementation and Nordic walking training favoured lowering the homocysteine (Hcy) level. Ninety-four elderly women were divided into three groups: Nordic walking (NW), supplemented (SG) and control (CG). The NW and SG groups received a weekly dose of 28,000 IU of vitamin D3. A blood analysis was performed at baseline, 1h after the first training session and at the end of the experiment. The amino acid profile (methionine and cysteine) and homocysteine concentration were determined. Additionally, the concentration of myokine was assessed. The first session of NW training reduced serum homocysteine, particularly among women with baseline homocysteine above 10 µmol·L −1 : 12.37 ± 2.75 vs. 10.95 ± 3.94 µmol·L −1 ( p = 0.05). These changes were accompanied by shifts in the cysteine ( p = 0.09) and methionine ( p = 0.01) concentration, regardless of the Hcy concentration. Twelve weeks of training significantly decreased the homocysteine (9.91 ± 2.78, vs. 8.90 ± 3.14 µmol·L −1 , p = 0.05) and ferritin (94.23 ± 62.49 vs. 73.15 ± 47.04 ng·mL −1 , p = 0.05) concentrations in whole NW group. Also, in the NW group, ferritin correlated with the glucose level (r = 0.51, p = 0.00). No changes in the myokine levels were observed after the intervention. Only the brain-derived neurotrophic factor dropped in the NW (42.74 ± 19.92 vs. 31.93 ± 15.91 ng·mL −1 , p = 0.01) and SG (37.75 ± 8.08 vs. 16.94 ± 12.78 ng·mL −1 , p = 0.00) groups. This study presents a parallel decrease of homocysteine and ferritin in response to regular training supported by vitamin D supplementation.

Keywords: physical training; methionine; cysteine; brain-derived neurotrophic factor (BDNF) (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
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