Long-Term Exposure to Air Pollutants and Cancer Mortality: A Meta-Analysis of Cohort Studies

Hong-Bae Kim, Jae-Yong Shim, Byoungjin Park and Yong-Jae Lee
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Hong-Bae Kim: Department of Family Medicine, MyongJi Hospital, Hanyang University Medical Center, 14-55 Hwasu-ro, Deokyang-gu, Goyang, Gyeonggi-do 10475, Korea
Jae-Yong Shim: Department of Medicine, Graduate School of Yonsei University, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul 03722, Korea
Byoungjin Park: Department of Medicine, Graduate School of Yonsei University, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul 03722, Korea
Yong-Jae Lee: Department of Medicine, Graduate School of Yonsei University, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul 03722, Korea

IJERPH, 2018, vol. 15, issue 11, 1-15

Abstract: The aim of this study was to examine the relationship between main air pollutants and all cancer mortality by performing a meta-analysis. We searched PubMed, EMBASE (a biomedical and pharmacological bibliographic database of published literature produced by Elsevier), and the reference lists of other reviews until April 2018. A random-effects model was employed to analyze the meta-estimates of each pollutant. A total of 30 cohort studies were included in the final analysis. Overall risk estimates of cancer mortality for 10 µg/m 3 per increase of particulate matter (PM) 2.5 , PM 10 , and NO 2 were 1.17 (95% confidence interval (CI): 1.11–1.24), 1.09 (95% CI: 1.04–1.14), and 1.06 (95% CI: 1.02–1.10), respectively. With respect to the type of cancer, significant hazardous influences of PM 2.5 were noticed for lung cancer mortality and non-lung cancer mortality including liver cancer, colorectal cancer, bladder cancer, and kidney cancer, respectively, while PM 10 had harmful effects on mortality from lung cancer, pancreas cancer, and larynx cancer. Our meta-analysis of cohort studies indicates that exposure to the main air pollutants is associated with increased mortality from all cancers.

Keywords: air pollutants; cancer mortality; cohort study; meta-analysis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (14)

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