Application of a Time-Stratified Case-Crossover Design to Explore the Effects of Air Pollution and Season on Childhood Asthma Hospitalization in Cities of Differing Urban Patterns: Big Data Analytics of Government Open Data

Ching-Yen Kuo, Ren-Hao Pan, Chin-Kan Chan, Chiung-Yi Wu, Dinh-Van Phan and Chien-Lung Chan
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Ching-Yen Kuo: Institute of Information Management, Yuan-Ze University, 135 Yuan-Tung Road, Jung-Li, Taoyuan 320, Taiwan
Ren-Hao Pan: Institute of Information Management, Yuan-Ze University, 135 Yuan-Tung Road, Jung-Li, Taoyuan 320, Taiwan
Chin-Kan Chan: Department of Pediatrics, Taoyuan General Hospital, Ministry of Health and Welfare, 1492 Zhongshan Road, Taoyuan Dist., Taoyuan 330, Taiwan
Chiung-Yi Wu: Institute of Information Management, Yuan-Ze University, 135 Yuan-Tung Road, Jung-Li, Taoyuan 320, Taiwan
Chien-Lung Chan: Institute of Information Management, Yuan-Ze University, 135 Yuan-Tung Road, Jung-Li, Taoyuan 320, Taiwan

IJERPH, 2018, vol. 15, issue 4, 1-15

Abstract: Few studies have assessed the lagged effects of levels of different urban city air pollutants and seasons on asthma hospitalization in children. This study used big data analysis to explore the effects of daily changes in air pollution and season on childhood asthma hospitalization from 2001 to 2010 in Taipei and Kaohsiung City, Taiwan. A time-stratified case-crossover study and conditional logistic regression analysis were employed to identify associations between the risk of hospitalization due to asthma in children and the levels of air pollutants (PM 2.5 , PM 10 , O 3 , SO 2 , and NO 2 ) in the days preceding hospitalization. During the study period, 2900 children in Taipei and 1337 in Kaohsiung aged ≤15 years were hospitalized due to asthma for the first time. The results indicated that the levels of air pollutants were significantly associated with the risk of asthma hospitalization in children, and seasonal effects were observed. High levels of air pollution in Kaohsiung had greater effects than in Taipei after adjusting for seasonal variation. The most important factor was O 3 in spring in Taipei. In children aged 0–6 years, asthma was associated with O 3 in Taipei and SO 2 in Kaohsiung, after controlling for the daily mean temperature and relative humidity.

Keywords: childhood asthma hospitalization; air pollution; time-stratified case-crossover design; urban pattern; big data and open data (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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