PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?

Alexandra Moraru, Maria Moitinho De Almeida and Jean-Marie Degryse
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Alexandra Moraru: Centre for Research on the Epidemiology of Disasters, Université Catholique de Louvain, Brussels 1200, Belgium
Maria Moitinho De Almeida: Centre for Research on the Epidemiology of Disasters, Université Catholique de Louvain, Brussels 1200, Belgium
Jean-Marie Degryse: Institute of Health and Society, Université Catholique de Louvain, Brussels 1200, Belgium

IJERPH, 2018, vol. 15, issue 5, 1-32

Abstract: Evidence suggests that nutritional status during fetal development and early life leaves an imprint on the genome, which leads to health outcomes not only on a person as an adult but also on his offspring. The purpose of this study is to bring forth an overview of the relevant parameters that need to be collected to assess the long-term and transgenerational health outcomes of famine. A literature search was conducted for the most pertinent articles on the epigenetic effects of famine. The results were compiled, synthesized and discussed with an expert in genetics for critical input and validation. Prenatal and early life exposure to famine was associated with metabolic, cardiovascular, respiratory, reproductive, neuropsychiatric and oncologic diseases. We propose a set of parameters to be collected in disaster settings to assess the long-term outcomes of famine: PALTEM (parameters to assess long-term effects of malnutrition).

Keywords: environmental epigenetics; DNA methylation; life-stage exposure; famine; risk assessment (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
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