Study of Factors Influencing the Bioaccessibility of Triazolone in Cherry Tomatoes Using a Static SHIME Model

Yu-Ying Liu, Jin-Jing Xiao, Yun-Yao Fu, Min Liao, Hai-Qun Cao and Yan-Hong Shi
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Yu-Ying Liu: School of Resource & Environment, Anhui Agricultural University, Hefei 230036, China
Jin-Jing Xiao: Provincial Key Laboratory for Agri-Food Safety, Anhui Agricultural University, Hefei 230036, China
Yun-Yao Fu: School of Plant Protection, Anhui Agricultural University, Hefei 230036, China
Min Liao: Provincial Key Laboratory for Agri-Food Safety, Anhui Agricultural University, Hefei 230036, China
Hai-Qun Cao: Provincial Key Laboratory for Agri-Food Safety, Anhui Agricultural University, Hefei 230036, China
Yan-Hong Shi: School of Resource & Environment, Anhui Agricultural University, Hefei 230036, China

IJERPH, 2018, vol. 15, issue 5, 1-10

Abstract: Estimating the influence of bioaccessibility of pesticide residues in fruits and vegetables on dietary exposure is a challenge for human health risk assessment. This study investigated the bioaccessibility of pesticide residues in cherry tomatoes and contributing factors (digestion time, pH, solid/liquid ratio, and dietary nutrition) using an in vitro test simulating the human gastrointestinal tract. pH had the largest effect on triazolone precipitation in the simulated gastric intestinal juice, which had a significant impact on the bioaccessibility. The bioaccessibility of triazolone in the intestinal stage was slightly higher than that in the stomach stage, owing to bile salts and pancreatic enzymes present in the intestinal juice. The bioaccessibility of triazolone did not change significantly with digestion time. In the gastric stage, there was a logarithmic relationship between the bioaccessibility and solid/liquid ratio (R 2 = 0.9941). The addition of oil significantly changed the bioaccessibility in the gastrointestinal stage. Protein and dietary fiber only affected bioaccessibility in the stomach stage. Dietary nutrition can reduce the release of pesticides from fruits and vegetables into the stomach, sharply reducing the bioaccessibility, and the dietary exposure of pesticide residues in fruits and vegetables can be properly evaluated.

Keywords: bioaccessibility; triazolone; cherry tomatoes; Simulator of the Human Intestinal Microbial Ecosystem (SHIME); risk assessment (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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