Alcoholism: A Multi-Systemic Cellular Insult to Organs

Ucee Dguzeh, Natasha C. Haddad, Kathia T. S. Smith, John O. Johnson, Angelia A. Doye, Judith K. Gwathmey and Georges E. Haddad
Additional contact information
Ucee Dguzeh: Department of Physiology, New Jersey Medical School Rutgers, 185 S Orange Ave, Newark, NJ 07103, USA
Natasha C. Haddad: Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA
Kathia T. S. Smith: Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA
John O. Johnson: Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA
Angelia A. Doye: Gwathmey Inc., Cambridge, MA 02138, USA
Judith K. Gwathmey: Gwathmey Inc., Cambridge, MA 02138, USA
Georges E. Haddad: Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA

IJERPH, 2018, vol. 15, issue 6, 1-12

Abstract: Alcohol abuse can affect more than the heart and the liver. Many observers often do not appreciate the complex and differing aspects of alcohol’s effects in pathophysiologies that have been reported in multiple organs. Chronic alcohol abuse is known to be associated with pathophysiological changes that often result in life-threatening clinical outcomes, e.g., breast and colon cancer, pancreatic disease, cirrhosis of the liver, diabetes, osteoporosis, arthritis, kidney disease, immune system dysfunction, hypertension, coronary artery disease, cardiomyopathy, and can be as far-reaching as to cause central nervous system disorders. In this review article, we will discuss the various organs impacted by alcohol abuse. The lack of clear guidelines on the amount and frequency of alcohol intake, complicated by personal demographics, make extrapolations to real-life practices at best difficult for public health policy-makers.

Keywords: alcohol abuse; alcohol beneficial effects; multi-organ effects of alcohol (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2018
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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